BOTULINAL NEUROTOXINS AS TOOLS IN STUDIES OF SYNAPTIC MECHANISMS
نویسندگان
چکیده
منابع مشابه
Synaptic vesicle chips to assay botulinum neurotoxins.
BoNTs (botulinum neurotoxins), considered to be the most toxic of all biological substances, inhibit neurotransmission through proteolytic cleavage of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins [VAMP (vesicle-associated membrane protein, or synaptobrevin), SNAP-25 (25 kDa synaptosome-associated protein) or syntaxin]. Expansion in the use of BoNTs as t...
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ژورنال
عنوان ژورنال: Quarterly Journal of Experimental Physiology
سال: 1989
ISSN: 0144-8757
DOI: 10.1113/expphysiol.1989.sp003329